August 2025
Articles published in Journal of Human Immunity
1: Bousfiha AA, Jeddane L, Moundir A, Poli MC, Aksentijevich I, Cunningham-Rundles C, et al. The 2024 update of IUIS phenotypic classification of human inborn errors of immunity. J Hum Immun. 2025 Apr 15;1(1):e20250002.
2: Kanegane H, Tanita K, Nishimura M, Tomomasa D, Inoue K, Kanamori T, et al. Revisiting X-linked agammaglobulinemia. J Hum Immun. 2025 Apr 28;1(1):e20250020.
3:Casanova JL. Human immunity. J Hum Immun. 2025 Feb 26;1(1):e20250001.
4: Poli MC, Aksentijevich I, Bousfiha AA, Cunningham-Rundles C, Hambleton S, Klein C, et al. Human inborn errors of immunity: 2024 update on the classification from the International Union of Immunological Societies Expert Committee. J Hum Immun. 2025 Apr 15;1(1):e20250003.
5: Hajjar J, Voigt AY, Conner ME, Swennes AG, Fowler S, Calarge C, et al. Gut dysbiosis patterns in CVID patients with noninfectious complications observed in a germ-free mouse model through fecal microbiota transplantation. J Hum Immun. 2025 Apr 23;1(1):e20250040.
6: Yamashita M, An Y, Bhattarai D, Eng-Binas VW, Homvises S, Ismail IH, et al. Healthcare resources for inborn errors of immunity in the Asia-Pacific region. J Hum Immun. 2025 May 13;1(2):e20250023.
High quality Articles published in 2025
1: Rider NL, Li Y, Chin AT, DiGiacomo DV, Dutmer C, Farmer JR, et al. Evaluating large language model performance to support the diagnosis and management of patients with primary immune disorders. J Allergy Clin Immunol. 2025 Feb 14;S0091-6749(25)00166-6.
2: Hiroki H, Moriya K, Uchiyama T, Hirose F, Endo A, Sato I, et al. A high-throughput TREC- and KREC-based newborn screening for severe inborn errors of immunity. Pediatr Int Off J Jpn Pediatr Soc. 2025;67(1):e15872.
3: Monahan R, Otani IM, Lehman HK, Mustafa SS. A second look at secondary hypogammaglobulinemia. Ann Allergy Asthma Immunol Off Publ Am Coll Allergy Asthma Immunol. 2025 Mar;134(3):269–78.
4: Ehlers L, Meyts I. Getting to know adenosine deaminase 2 deficiency inside and out. J Allergy Clin Immunol. 2025 May;155(5):1451–63.
5: Noma K, Asano T, Taniguchi M, Ashihara K, Okada S. Anti-cytokine autoantibodies in human susceptibility to infectious diseases: insights from Inborn errors of immunity. Immunol Med. 2025 Apr 8;1–17.
6: Zuraw BL, Bork K, Bouillet L, Christiansen SC, Farkas H, Germenis AE, et al. Hereditary Angioedema with Normal C1 Inhibitor: an Updated International Consensus Paper on Diagnosis, Pathophysiology, and Treatment. Clin Rev Allergy Immunol. 2025 Mar 7;68(1):24.
7: Cohn DM, Gurugama P, Magerl M, Katelaris CH, Launay D, Bouillet L, et al. CRISPR-Based Therapy for Hereditary Angioedema. N Engl J Med. 2025 Jan 30;392(5):458–67.
8: Wijeyesinghe S, Chinen J. Gene therapy for inborn errors of immunity: Current clinical progress. Ann Allergy Asthma Immunol Off Publ Am Coll Allergy Asthma Immunol. 2025 Mar 8;S1081-1206(25)00117-6.
9: Fekrvand S, Saleki K, Abolhassani H, Almasi-Hashiani A, Hakimelahi A, Zargarzadeh N, et al. COVID-19 infection in inborn errors of immunity and their phenocopies: a systematic review and meta-analysis. Infect Dis Lond Engl. 2025 Jun;57(6):483–517.
10: Giardino G, Di Matteo G, Giliani S, Ferrari S, Lougaris V, Badolato R, et al. Consensus of the Italian Primary Immunodeficiency Network on the use and interpretation of genetic testing for diagnosing inborn errors of immunity. J Allergy Clin Immunol. 2025 Apr;155(4):1149–60.
11: Saeidi Z, Fadai S, Mesdaghi M, Mirzaee AZ, Sharafian S, Rahmani K, et al. Rheumatologic manifestations in children with underlying inborn errors of immunity. BMC Rheumatol. 2025 May 23;9(1):57.
Articles on IEI originating from India in 2025
1: Barman P, Kaur A, Chawla S, Sil A, Dhaliwal M, Rawat A, et al. Utility of simultaneous quantification of TREC/KREC in patients with common variable immunodeficiency phenotype: an observational study from North India. Immunol Res. 2025 Mar 17;73(1):63.
2: Vignesh P, Singh S. Secondary Hypogammaglobulinemia: An Under-Recognized Clinical Entity in Children. Indian Pediatr. 2025 May 12.
Information and links to significant upcoming International and National IEI meetings
1: ESID School 2025, 22-25 May 2025, Barcelona https://esid.org/esid-summer-school-2025/
2: IIC Oxford 2025, 23-25 June 2025, Oxford, UK https://www.oxfordiic.org/
3: CIS Diagnostic School (Virtual), 17-18 July 2025, Virtual https://clinimmsoc.org/CIS/Meetings/Diagnostic-School1.htm
4: CIS summer school, 9-12 October, 2025, Florida, USA https://clinimmsoc.org/CIS/Meetings/Summer-School.htm
5: IPIC 2025, November 5-7 2025, Prague, Czech Republic https://ipic2025.com/
6: ESID, 2026, 14-17 October 2026, Maastricht, the Netherlands https://esidmeeting.org/